Jihae Sophia Lee | she/her

Jihae Sophia Lee | she/her

An bioinformatician & neuroscientist interested in nerodevelopment, neurological disorders, and stem cell derived models. Loves nature, people, dogs, and tennis

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Pages

Posts

To be Updated!

less than 1 minute read

Published:

Going to be updated with my experiences..!

portfolio

[Poster]: Brain Organoid Cell Type Prediction by Brain Single-cell Atlas Trained Annotation Models

- Annual Meeting of the Korean Society for Molecular and Cellular Biology (KSMCB) Neurodevelopment Division, Busan, Korea (July 2024)
- Annual Meeting of the Korean Society for Brain and Neural Sciences in conjunction with the Biennial Meeting of the Asian-Pacific Society for Neurochemistry (KSBNS-ASPN), Gyeongju, Korea (October 2024)
- Annual Meeting of the Korean Society for Bioinformatics (KSBI), Gyeongju, Korea (October 2024)

[Poster]: Comparison of Downstream Analysis of MERFISH and Visium Mouse Brain Samples

- Seoul University Cancer Institute Winter Internship Poster

publications

[An integrative single-cell atlas for exploring the cellular and temporal specificity of genes related to neurological disorders during human brain development]

Published in Experimental & Molecular Medicine, 2024

Link to the paper: https://www.nature.com/articles/s12276-024-01328-6
atlas_fig1
This study introduced the expression dynamics of neurological risk genes through human brain development by constructing a single-cell human brain atlas.
We have uncovered distinct expression patterns of neurological disorder risk genes within cell differentiation trajectories and investigated the gene regulatory mechanisms during early brain development.

Please check our Zenodo for the Anndata and Seurat object of the atlas and gene dynamics plot for 3380 neurological risk genes!

Download Paper

talks